Product Overview & China Production Capacity
Heptane (n-Heptane, CAS 142-82-5, molecular formula C₇H₁₆, MW 100.20) is a high-purity nonpolar alkane solvent widely used in pharmaceutical manufacturing for API extraction, crystallization, chromatographic purification, and as a reaction medium in synthetic chemistry. In analytical applications, HPLC-grade heptane serves as a mobile phase component for normal-phase chromatography. As a pharmaceutical excipient, residual heptane is classified as ICH Class 3 (low toxicity) with a PDE of 50 mg/day.
China’s petrochemical industry produces large volumes of pharmaceutical-grade heptane through catalytic reformate fractionation. Our refinery in Liaoning Province operates a dedicated high-purity heptane distillation unit with 20,000 MT/year capacity, producing n-heptane at ≥99.0% purity through precision fractional distillation of light naphtha cuts.
Manufacturing Standards & Quality Assurance
Production operates under ISO 9001:2015 quality management with pharmaceutical solvent quality compliance. The product meets ACS reagent grade, HPLC grade, and pharmacopeial requirements for n-Heptane. Our fractionation process achieves isomeric purity control with minimal branched-chain heptane isomers and aromatic impurities.
Quality testing includes GC assay and purity (capillary column analysis), residue on evaporation, water content (Karl Fischer), acidity/alkalinity, color (APHA), sulfur content, UV absorbance (cutoff wavelength for HPLC grade), and specific gravity. Each batch is tested for benzene content (<1 ppm) to ensure safety compliance.
Technical Specifications
| Parameter | Specification |
|---|---|
| Appearance | Clear, colorless liquid |
| Assay (GC, n-Heptane) | ≥99.0% |
| Boiling Range | 97–99°C |
| Specific Gravity (20°C) | 0.683–0.686 |
| Refractive Index (20°C) | 1.387–1.389 |
| Water Content | ≤0.01% |
| Residue on Evaporation | ≤0.001% |
| Acidity (as CH₃COOH) | ≤0.0005% |
| Sulfur | ≤1 ppm |
| Benzene | ≤1 ppm |
Packaging & Export Logistics
Supplied in 160 kg steel drums (UN-rated for flammable liquids), 800 kg IBC totes, or ISO tank containers for bulk orders. Store in a cool, well-ventilated area away from ignition sources at 15–25°C. Keep containers tightly sealed. Shelf life is 36 months. Classified as Dangerous Goods: UN 1206, Class 3, Packing Group II — all shipments comply with IMDG/ADR/IATA transport regulations.
We export from Dalian and Shanghai ports with DG-certified freight forwarding services. ISO tank shipments available for volumes exceeding 15 MT. Complete DG documentation including MSDS, UN test report, and transport emergency cards provided with every shipment.
China Supply Advantage
China’s large-scale petrochemical refining infrastructure enables pharmaceutical-grade heptane pricing 30–45% below European and US specialty solvent producers. Our integrated naphtha fractionation process provides consistent quality and reliable supply from one of the world’s largest refining regions.
MOQ is 1,000 kg (approximately 6 drums) with 7–10 business day lead time. Bulk ISO tank pricing is available for annual contracts. We offer both standard pharmaceutical grade and HPLC grade with UV cutoff certification. Our logistics team specializes in dangerous goods export handling for all transport modes. Contact us for competitive pricing on pharmaceutical-grade solvents.