Product Overview & China Production Capacity
Povidone K30 (PVP K30, CAS 84057-81-8, MW ~40,000–54,000) is a water-soluble synthetic polymer of N-vinylpyrrolidone widely used as a binder, film-former, solubilizer, and suspending agent in pharmaceutical formulations. China has emerged as a major global producer of pharmaceutical-grade Povidone, with annual capacity exceeding 30,000 metric tons from production facilities in Henan, Shanghai, and Jiangsu provinces. Manufacturer-direct supply from China delivers consistent quality at highly competitive pricing.
Povidone K30 is the most frequently specified grade for wet granulation binding in tablet manufacturing, providing excellent granule strength and compressibility. It also functions as a crystallization inhibitor in amorphous solid dispersions, a solubilizer for poorly water-soluble APIs, and a viscosity modifier in liquid formulations. Chinese manufacturers produce PVP K30 through free-radical polymerization of N-vinylpyrrolidone in aqueous or organic solvent systems, achieving precise K-value targeting through controlled initiator addition and reaction conditions.
Manufacturing Standards & Quality Assurance
Production facilities maintain ISO 9001:2015, and cquality certifications compliant with FDA inspection standards. Quality testing includes K-value determination (capillary viscometry), residual monomer (N-vinylpyrrolidone) analysis by GC, aldehyde content, heavy metals, pH, loss on drying, residue on ignition, and microbial limits. All batches meet USP/NF, EP, JP, and ChP monograph specifications. Active DMF registrations with the US FDA are maintained.
Polymerization reactors are equipped with automated monomer dosing, temperature control, and nitrogen blanketing systems. Post-polymerization processing includes spray drying to achieve target particle size and moisture content. Residual monomer levels are reduced to below 10 ppm through optimized drying conditions and post-treatment protocols.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 84057-81-8 |
| K-Value | 27.0–32.4 |
| Average Molecular Weight | 40,000–54,000 |
| Appearance | White to yellowish-white powder |
| Loss on Drying | ≤5.0% |
| Residual Monomer (VP) | ≤10 ppm |
| pH (5% aqueous) | 3.0–7.0 |
| Aldehydes | ≤500 ppm |
| Heavy Metals | ≤10 ppm |
| Pharmacopoeial Compliance | USP/NF, EP, JP, ChP |
Packaging & Export Logistics
Povidone K30 is supplied in 25 kg PE-lined fiber drums or 25 kg aluminum foil bags, stored and transported in moisture-controlled conditions. Bulk packaging in 50 kg drums or custom sizes is available. Lead time is 10–14 business days from order confirmation. Shipments from Shanghai, Qingdao, or Shenzhen ports under FOB, CIF, or DDP Incoterms.
Each shipment includes CoA, SDS, DMF reference letter, and regulatory compliance documentation. Moisture-protective packaging options are available for shipments to high-humidity destinations.
China Supply Advantage
Chinese Povidone K30 producers deliver pharma-grade material at 25–40% below Western manufacturer pricing through integrated N-vinylpyrrolidone monomer production and polymerization operations. Established export relationships with pharmaceutical companies in over 60 countries demonstrate consistent quality performance. Direct sourcing eliminates distributor margins and provides access to technical support teams experienced in tablet formulation optimization and solid dispersion development.