Resveratrol 501-36-0 — China Manufacturer | Natural Extract R&D to Production

Product Overview & China Production Capacity

Resveratrol (trans-3,5,4’-trihydroxystilbene, CAS 501-36-0, molecular formula C₁₄H₁₂O₃, MW 228.24) is a polyphenolic stilbenoid compound found in grapes, Japanese knotweed (Polygonum cuspidatum), and peanuts, recognized for its antioxidant, cardioprotective, and anti-aging properties. China is the world’s largest resveratrol producer with annual capacity exceeding 3,000 metric tons, primarily extracted from Polygonum cuspidatum root at facilities in Shaanxi, Hubei, Guizhou, and Hunan provinces. Manufacturer-direct supply delivers pharmaceutical and nutraceutical-grade resveratrol at globally competitive pricing.

Resveratrol activates sirtuin-1 (SIRT1) and AMP-activated protein kinase (AMPK) pathways, providing cellular anti-aging and metabolic benefits. Applications span dietary supplements, pharmaceutical research, functional foods, and cosmetic anti-aging formulations. Chinese manufacturers offer natural trans-resveratrol in standardized extracts (50%, 98%) and synthetic resveratrol (≥99% HPLC) for different market segments and price points.

Manufacturing Standards & Quality Assurance

Production facilities hold ISO 9001:2015, ISO 22000, HACCP, organic (USDA NOP, EU), and kosher/halal certifications. Quality testing includes trans-resveratrol content (HPLC), emodin content (must be controlled for P. cuspidatum extracts), moisture, ash, heavy metals (Pb, Cd, As, Hg by ICP-MS), pesticide residues, solvent residues, PAHs, and microbial limits. Products comply with USP dietary supplement standards and meet EU Novel Food requirements.

Extraction from P. cuspidatum root uses ethanol or water-ethanol systems followed by macroporous resin purification, concentration, and crystallization. High-purity (≥98%) trans-resveratrol undergoes additional recrystallization steps. Emodin (an anthraquinone co-extractive) is removed through selective adsorption chromatography to meet regulatory limits. Trans/cis isomer ratio is monitored by HPLC to ensure predominantly trans-configuration.

Technical Specifications

ParameterSpecification
CAS Number501-36-0
Molecular FormulaC₁₄H₁₂O₃
Molecular Weight228.24 g/mol
AppearanceWhite to off-white powder (high purity) / brown powder (extract)
trans-Resveratrol (HPLC)50% / 98% / ≥99%
SourcePolygonum cuspidatum root extract
Emodin Content<1 ppm (high purity grades)
Moisture≤5.0%
Heavy Metals (Pb)≤2 ppm
CertificationsOrganic, Kosher, Halal available

Packaging & Export Logistics

Resveratrol is packed in 1 kg, 5 kg, or 25 kg aluminum foil bags within fiber drums, stored under cool, dry, light-protected conditions with nitrogen flushing for oxidation-sensitive high-purity grades. Lead time is 7–14 business days. FOB from Shanghai, Xi’an, or Guangzhou; CIF and DDP terms available.

Light and oxygen-protective packaging is essential for maintaining trans-resveratrol stability. Documentation includes CoA, SDS, organic certificates, and phytosanitary certificates.

China Supply Advantage

China’s abundant Polygonum cuspidatum wild and cultivated resources provide the most cost-effective resveratrol production globally, delivering competitive pricing 30–50% below other sources. Advanced purification technology enables production of emodin-free, high-purity trans-resveratrol meeting the most demanding quality specifications. Chinese resveratrol producers serve supplement, pharmaceutical, and cosmetic companies worldwide with consistent quality and responsive R&D support.

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