Product Overview & China Production Capacity
Polyethylene Glycol 1000 (PEG 1000, CAS 25322-68-3, average MW ~1,000) is a waxy solid polyether polymer used as a suppository base, ointment component, solubilizer, and plasticizer in pharmaceutical formulations. China’s PEG manufacturing capacity exceeds 1.5 million metric tons annually across all molecular weight grades, with PEG 1000 produced in continuous ethylene oxide polymerization reactors at facilities in Jiangsu, Liaoning, and Shandong provinces. This large-scale production enables highly competitive competitive pricing for global pharmaceutical and cosmetic buyers.
PEG 1000 occupies a unique position in the PEG molecular weight range, exhibiting a paste-to-waxy solid consistency at room temperature. It serves as a hydrophilic ointment base, a component in suppository formulations blended with higher MW PEGs, and a solubilizing agent for poorly water-soluble drugs in solid dispersion systems. Chinese manufacturers produce PEG 1000 meeting USP/NF and EP specifications through carefully controlled ring-opening polymerization with narrow molecular weight distribution.
Manufacturing Standards & Quality Assurance
PEG 1000 production facilities operate under ISO 9001:2015, and kosher/halal certifications. Quality testing includes average molecular weight determination (hydroxyl value), ethylene glycol and diethylene glycol residue analysis (GC), heavy metals testing, water content (Karl Fischer), pH measurement, and microbial limits. All grades meet USP/NF, EP, and ChP monograph specifications.
Ethylene oxide feedstock quality is verified prior to each polymerization campaign. In-process monitoring tracks reaction temperature, pressure, and catalyst concentration. Finished product is analyzed for color, odor, hydroxyl value, and consistency before release. Retained samples and batch documentation are maintained for a minimum of three years.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 25322-68-3 |
| Average Molecular Weight | 950–1,050 |
| Appearance | White to off-white waxy solid |
| Hydroxyl Value | 107–118 mg KOH/g |
| pH (5% aqueous) | 4.5–7.5 |
| Water Content | ≤1.0% |
| Ethylene Glycol + DEG | ≤0.25% |
| Heavy Metals | ≤10 ppm |
| Residue on Ignition | ≤0.1% |
| Pharmacopoeial Compliance | USP/NF, EP, ChP |
Packaging & Export Logistics
PEG 1000 is supplied in 25 kg kraft paper bags with PE liners or 50 kg fiber drums, palletized for container loading. Bulk orders can be arranged in 200 kg drums or molten isotank delivery. Packaging materials meet food-contact standards per FDA 21 CFR and EU regulations. Lead time is 10–15 business days from confirmed order, with shipments available from Shanghai, Dalian, and Qingdao.
Standard documentation includes CoA, SDS, and regulatory compliance certificates. Temperature-controlled shipping can be arranged for warm-climate destinations to prevent product softening during transit.
China Supply Advantage
China’s massive ethylene oxide production infrastructure supports PEG manufacturing at scales unmatched elsewhere, delivering cost advantages of 25–40% for pharma-grade PEG 1000. Established export relationships with pharmaceutical companies in over 50 countries ensure smooth logistics and regulatory documentation. Direct sourcing provides access to full technical support including formulation guidance, custom molecular weight blending, and stability data packages to support product development timelines.