Product Overview & China Production Capacity
Polyethylene Glycol 1500 (PEG 1500, CAS 25322-68-3, average MW ~1,500) is a solid-grade polyether widely utilized as a suppository base, tablet binder, and hydrophilic carrier in pharmaceutical dosage forms. Chinese manufacturers produce PEG 1500 in dedicated polymerization reactors capable of achieving narrow molecular weight distributions, with combined national capacity supporting tens of thousands of metric tons of pharmaceutical-grade PEG 1500 annually. Major production sites are located in Jiangsu, Shandong, and Liaoning provinces.
PEG 1500 provides an optimal balance between hardness and flexibility for suppository formulations, either alone or blended with PEG 4000 and PEG 6000. In solid dosage forms, it functions as a binder in wet granulation and as a hydrophilic matrix for sustained-release formulations. Its water solubility, biocompatibility, and well-characterized safety profile make PEG 1500 a preferred excipient for topical, oral, and rectal pharmaceutical products.
Manufacturing Standards & Quality Assurance
Manufacturing is conducted under China pharmaceutical conditions with ISO 9001:2015 quality systems. Testing protocols cover average molecular weight (hydroxyl value titration), ethylene glycol and diethylene glycol residual content (GC), pH, water content, color, and heavy metals. Products comply with USP/NF, EP, and ChP monograph requirements. FDA DMF registrations and EDQM CEP filings are maintained by major producers.
Polymerization conditions including catalyst type, reaction temperature, and ethylene oxide feed rate are precisely controlled to ensure batch-to-batch consistency. Post-reaction purification removes catalyst residues and low-MW oligomers. Each batch is quarantined pending full analytical release by the QC department.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 25322-68-3 |
| Average Molecular Weight | 1,400–1,600 |
| Appearance | White waxy solid |
| Hydroxyl Value | 71–80 mg KOH/g |
| pH (5% aqueous) | 4.5–7.5 |
| Water Content | ≤1.0% |
| Ethylene Glycol + DEG | ≤0.25% |
| Heavy Metals | ≤10 ppm |
| Color (APHA, molten) | ≤20 |
| Pharmacopoeial Compliance | USP/NF, EP, ChP |
Packaging & Export Logistics
PEG 1500 is packed in 25 kg PE-lined kraft bags or 50 kg fiber drums, palletized and shrink-wrapped for ocean container loading. Bulk supply in 200 kg drums or 1 MT FIBCs is available upon request. Lead time is 10–14 business days. FOB shipment from Shanghai, Qingdao, or Dalian ports; CIF and DDP terms are also supported.
Each shipment includes CoA, SDS, packing list, and commercial invoice. Regulatory dossier support documentation can be provided for customers requiring pharmacopoeial compliance evidence for registration filings.
China Supply Advantage
Sourcing PEG 1500 from Chinese manufacturers delivers landed-cost savings of 20–35% while maintaining full pharmacopoeial compliance. China’s petrochemical infrastructure ensures uninterrupted ethylene oxide supply, providing production stability that translates to reliable delivery performance. Long-standing export relationships with pharmaceutical companies across Asia, Europe, the Americas, and Africa demonstrate the quality consistency and commercial reliability of Chinese PEG producers. Direct manufacturer engagement ensures rapid sample provision, competitive MOQs, and dedicated technical support.