Suzhou Pharmaceutical Technology Co., Ltd. (China) supplies Tacrolimus API CAS 104987-11-3 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Tacrolimus API — Overview
Tacrolimus (CAS: 104987-11-3, also known as FK506, Fujimycin, tacrolimus anhydrous, Prograf active ingredient, Protopic active ingredient, and Tsukubaenolide) is a calcineurin-inhibitor immunosuppressant API used in transplant, dermatology, and research formulation programs where local regulations permit. Suzhou Pharmaceutical Technology Co., Ltd. supplies Tacrolimus API in bulk from Suzhou, China, with export to South America, Australia, New Zealand, Mexico, Canada, and worldwide markets. Export documentation: COA and MSDS standard for all orders.
| Product Name | Tacrolimus |
| Structural Formula |  |
| Alias | FK506; Fujimycin; Tacrolimus anhydrous; Prograf active ingredient; Protopic active ingredient; Tsukubaenolide |
| CAS Number | 104987-11-3 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.0 g/mol |
| Purity | Available by agreed HPLC specification |
| Appearance | White to off-white crystalline powder |
| Storage | Store sealed, protected from light, heat, and moisture |
> Applications
Tacrolimus is used by pharmaceutical manufacturers and research groups developing immunosuppressant and topical dermatology products. API supply is intended for qualified buyers who will confirm dosage form, indication language, impurity requirements, pharmacopoeial strategy, and finished-dose registration obligations in their own markets.
Dermatology formulation research
A 2005 journal article reported three randomized comparative studies of tacrolimus ointment and pimecrolimus cream in adult and pediatric atopic dermatitis patients (J Am Acad Dermatol, doi:10.1016/j.jaad.2004.12.038, PMID:15858471, n=1065). This supports Tacrolimus API relevance for topical calcineurin-inhibitor formulation research.
Transplant and immunosuppressant development
Buyers typically evaluate assay, related substances, residual solvents, water content, polymorphic behavior, particle properties, and stability data before moving from sample quantities to pilot or commercial batches. We supply API only, not finished capsules, injections, granules, ointments, or ophthalmic products.
> Sourcing & Supply
Suzhou Pharmaceutical Technology Co., Ltd. is an R&D-driven pharmaceutical company with in-house synthesis and analytical capability for Tacrolimus API. Small batches (up to 10 kg) are produced directly by our technical team in Suzhou. For larger commercial quantities, production is scaled up at qualified manufacturing facilities, with export documentation provided according to the order scope.
- Small-batch orders (≤10 kg): prepared by our technical team in Suzhou. Lead time 10–14 business days from order confirmation.
- Commercial bulk (>10 kg): scaled up at qualified manufacturing facilities. Lead time 14–21 business days depending on batch size and documentation.
We export Tacrolimus API to buyers across South America — including Brazil, Argentina, Colombia, Chile, Peru, Ecuador, Bolivia, Paraguay, and Uruguay — as well as to Australia, New Zealand, Mexico, and Canada. Inquiries from European, Middle Eastern, and Asian markets are also welcome.
> Quality & Export Documentation
All Tacrolimus shipments are accompanied by a Certificate of Analysis (COA) confirming identity, appearance, assay, and related substances against batch specification. Purity is tested by HPLC against an authenticated reference standard. MSDS is provided for all orders, and Certificate of Origin (COO) is available for commercial bulk shipments.
| Order size | Documentation included |
| ≤10 kg (small-batch / research) | COA + MSDS |
| >10 kg (commercial bulk) | COA + MSDS + COO |
> Packaging & Logistics
- 10 g, 50 g: amber glass bottle or double-layered aluminium foil bag
- 100 g, 500 g: aluminium foil bag, heat-sealed, nitrogen-purged
- 1 kg, 5 kg: aluminium foil bag inside fibre drum or insulated carton
- >10 kg: packaging agreed according to commercial order requirements
Tacrolimus API is shipped with light-, heat-, and moisture-protective packaging and batch labels matched to the COA. Shipping options include express courier for sample and kilogram quantities, air freight for 1–10 kg orders, and sea freight for larger commercial shipments where timing allows.
> Pricing & Supply
Tacrolimus pricing is provided on request. We do not publish list prices because the final quote depends on order quantity, purity requirement, documentation needs, shipping destination, and current raw material costs.
- MOQ: 10 g for qualified buyers
- Sample policy: 1–5 g samples available for analytical confirmation
- Bulk discount tiers apply at 100 g, 500 g, 1 kg, and 5 kg
- Payment: T/T (bank transfer). 100% in advance for standard orders. Terms for larger repeat orders by arrangement.
> Frequently Asked Questions
What is the minimum order quantity for Tacrolimus API?
The minimum order quantity for Tacrolimus API is 10 grams. Small samples of 1–5 g are available for qualified analytical evaluation.
What documents are included with a Tacrolimus bulk order?
All Tacrolimus orders include a COA and MSDS in English. For commercial bulk orders above 10 kg, COO is available as standard export documentation.
Can I request a Tacrolimus sample before placing a bulk order?
Yes. Sample quantities of 1–5 g are available for qualified buyers before pilot or commercial orders.
Do you export Tacrolimus API to South America?
Yes. We support Tacrolimus API inquiries from Brazil, Argentina, Colombia, Chile, Peru, Ecuador, Bolivia, Paraguay, and Uruguay.
Can buyers in Australia, New Zealand, Mexico, or Canada order Tacrolimus?
Yes. We supply Tacrolimus API to buyers in Australia, New Zealand, Mexico, and Canada. COA and MSDS are included with all orders.
What is Tacrolimus used for?
Tacrolimus is used as a calcineurin-inhibitor immunosuppressant API for transplant and dermatology products where local regulations allow.
What is the mechanism of action of Tacrolimus?
Tacrolimus binds FKBP-12 and inhibits calcineurin signaling, reducing T-cell activation and cytokine transcription.
Is Prograf the same as Tacrolimus?
Prograf is a finished medicine brand whose active ingredient is tacrolimus. We supply bulk Tacrolimus API, not finished medicine products.
What specification is available for Tacrolimus CAS 104987-11-3?
Tacrolimus is supplied by agreed HPLC specification, including assay and related-substance controls defined before order confirmation.
How is Tacrolimus packaged and shipped internationally?
Tacrolimus API is shipped in light- and moisture-protective packaging, with added thermal protection when route or season requires it.
> Related Products
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- Hydrocortisone | CAS 74050-20-7 — corticosteroid API
- Tofacitinib Citrate | CAS 540737-29-9 — JAK inhibitor API
> Request a Quote or Sample
To request a quote or sample for Tacrolimus API (CAS 104987-11-3), please contact us directly at Info@fmyykj.com.
Include in your inquiry: required quantity (grams or kg), destination country, documentation requirements (COA + MSDS standard; COO for bulk), and intended use (formulation / analytical development / research / other). We respond to all inquiries within 1 business day.
Last reviewed: June 2026