Suzhou Pharmaceutical Technology Co., Ltd. (China) supplies Toceranib Phosphate API CAS 874819-74-6 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Toceranib Phosphate API — Overview
Toceranib phosphate (CAS: 874819-74-6, also known as SU11654, PHA-291639E, and Palladia active ingredient) is a multi-target receptor tyrosine kinase inhibitor API used in veterinary oncology formulation and research. It inhibits targets including KIT, VEGFR, and PDGFR pathways relevant to canine mast cell tumor biology. Suzhou Pharmaceutical Technology Co., Ltd. supplies ≥98% Toceranib phosphate API in bulk from Suzhou, China, with export to South America, Australia, New Zealand, Mexico, Canada, and worldwide markets. Export documentation: COA and MSDS standard for all orders.
| Product Name | Toceranib phosphate |
| Structural Formula |  |
| Alias | SU11654; SU 11654; PHA-291639E; PHA291639; Palladia active ingredient |
| CAS Number | 874819-74-6 |
| Molecular Formula | C₂₂H₂₈FN₄O₆P |
| Molecular Weight | 494.5 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to light yellow powder |
| Storage | Store sealed, protected from light and moisture |
> Applications
Toceranib phosphate is used by veterinary pharmaceutical companies, compounding pharmacies, and research organizations working on canine oncology formulations where local regulations permit. As a small-molecule tyrosine kinase inhibitor, it is relevant to programs studying KIT-driven mast cell tumors and antiangiogenic targets such as VEGFR and PDGFR.
Canine mast cell tumor research and formulation
In a multicenter, placebo-controlled, double-blind, randomized study of dogs with recurrent mast cell tumors after surgical excision, oral toceranib phosphate showed antitumor activity and an objective response rate of 42.8% in the blinded phase (Clinical Cancer Research, 2009, doi:10.1158/1078-0432.CCR-08-1860). The study reported inhibition of KIT, VEGFR2, and PDGFRβ as key pharmacologic targets, supporting API relevance for veterinary oncology development.
Veterinary oncology API use
API buyers usually evaluate assay, related substances, geometric isomer control, residual palladium, residual solvents, particle size, and stability data before moving from sample quantities to pilot or commercial batches. Finished-dose development, registration, sale, and clinical use remain subject to the buyer’s local veterinary medicine regulations.
> Sourcing & Supply
Suzhou Pharmaceutical Technology Co., Ltd. is an R&D-driven pharmaceutical company with in-house synthesis and analytical capability for Toceranib phosphate API. Small batches (up to 10 kg) are produced directly by our technical team in Suzhou. For larger commercial quantities, production is scaled up at qualified manufacturing facilities, with export documentation provided according to the order scope.
- Small-batch orders (≤10 kg): synthesized by our technical team in Suzhou. Lead time 10–14 business days from order confirmation.
- Commercial bulk (>10 kg): scaled up at qualified manufacturing facilities. Lead time 14–21 business days depending on batch size and documentation.
We export Toceranib phosphate API to buyers across South America — including Brazil, Argentina, Colombia, Chile, Peru, Ecuador, Bolivia, Paraguay, and Uruguay — as well as to Australia, New Zealand, Mexico, and Canada. Inquiries from European, Middle Eastern, and Asian markets are also welcome.
> Quality & Export Documentation
All Toceranib phosphate shipments are accompanied by a Certificate of Analysis (COA) confirming identity, appearance, assay, and related substances against batch specification. Purity is tested by HPLC against an authenticated reference standard. MSDS is provided for all orders, and Certificate of Origin (COO) is available for commercial bulk shipments.
| Order size | Documentation included |
| ≤10 kg (small-batch / research) | COA + MSDS |
| >10 kg (commercial bulk) | COA + MSDS + COO |
> Packaging & Logistics
- 100 g, 500 g: double-layered aluminium foil bag, heat-sealed, nitrogen-purged
- 1 kg: aluminium foil bag inside kraft paper box
- 5 kg, 10 kg: aluminium foil bag inside fibre drum
- >10 kg: packaging agreed according to commercial order requirements
Toceranib phosphate API is shipped with light- and moisture-protective packaging and batch labels matched to the COA. Shipping options include express courier for sample and kilogram quantities, air freight for 1–10 kg orders, and sea freight for larger commercial shipments where timing allows.
> Pricing & Supply
Toceranib phosphate pricing is provided on request. We do not publish list prices because the final quote depends on order quantity, purity requirement, documentation needs, shipping destination, and current raw material costs.
- MOQ: 100 g for qualified buyers
- Sample policy: 10–50 g samples available for formulation evaluation or analytical confirmation
- Bulk discount tiers apply at 500 g, 1 kg, 5 kg, and 10 kg
- Payment: T/T (bank transfer). 100% in advance for standard orders. Terms for larger repeat orders by arrangement.
> Frequently Asked Questions
What is the minimum order quantity for Toceranib phosphate API?
The minimum order quantity for Toceranib phosphate API is 100 grams. Sample quantities of 10–50 g are available for qualified buyers before pilot or commercial orders.
What documents are included with a Toceranib phosphate bulk order?
All Toceranib phosphate orders include a COA and MSDS in English. For commercial bulk orders above 10 kg, COO is available as standard export documentation.
Can I request a Toceranib phosphate sample before placing a bulk order?
Yes. Sample quantities of 10–50 g are available for qualified buyers. Samples are normally dispatched within 7 business days of inquiry confirmation.
Do you export Toceranib phosphate API to South America?
Yes. We support Toceranib phosphate API inquiries from Brazil, Argentina, Colombia, Chile, Peru, Ecuador, Bolivia, Paraguay, and Uruguay.
Can buyers in Australia, New Zealand, Mexico, or Canada order Toceranib phosphate?
Yes. We supply Toceranib phosphate API to buyers in Australia, New Zealand, Mexico, and Canada. COA and MSDS are included with all orders.
What is Toceranib phosphate used for in veterinary medicine?
Toceranib phosphate is used as a veterinary oncology active ingredient related to canine mast cell tumor treatment where approved by local regulations.
What is the mechanism of action of Toceranib phosphate?
Toceranib phosphate is a multi-target receptor tyrosine kinase inhibitor with activity against targets including KIT, VEGFR, and PDGFR pathways.
Is Palladia the same as Toceranib phosphate?
Palladia is a finished veterinary medicine whose active ingredient is toceranib phosphate. We supply bulk API, not finished tablets.
What purity is available for Toceranib phosphate CAS 874819-74-6?
Our standard Toceranib phosphate API specification is ≥98% purity by HPLC. Each batch is released with a COA covering agreed specification items.
How is Toceranib phosphate packaged and shipped internationally?
Toceranib phosphate API is shipped in foil bags or foil-lined fibre drums with protection from light and moisture during international transit.
> Related Products
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- Pimobendan | CAS 74150-27-9 — Veterinary cardiac API
> Request a Quote or Sample
To request a quote or sample for Toceranib phosphate API (CAS 874819-74-6), please contact us directly at Info@fmyykj.com.
Include in your inquiry: required quantity (grams or kg), destination country, documentation requirements (COA + MSDS standard; COO for bulk), and intended use (veterinary formulation / compounding / research / other). We respond to all inquiries within 1 business day.
Last reviewed: June 2026